The ‘yellow’ ingredients: Banaba leaf extract, Bilberry fruit extract, Bitter melon fruit extract, Cinnamon bark extract, Chromium, Fenugreek seed extract, Gymnema Sylvestre leaf extract, Jambolan fruit extract, Pterocarpus marsupium bark extract, Tinospora Cordifolia leaf extract, Vanadyl sulfate, and Zinc.
Propionate produced in the gut as a result of bacterial fermentation reduces energy intake and appetite, regulates adipogenesis, and reduces adipose tissue inflammation, finally resulting in weight loss.
Vitamin C decreases weight by increasing fat metabolism by 30% and reducing the inflammation of adipocytes. Vitamin C also increases the concentration of adiponectin, leptin, and insulin sensitivity.
Vitamin C decreases cravings by improving glycemic control and repairing and protecting brain centers responsible for serotonin and leptin sensitivity.
Vitamin C improves diabetes control by improving insulin sensitivity, glycemic control, oxidative stress, and immune responses.
Tyramine reduces cravings by increasing the concentration of dopamine and norepinephrine.
Tyramine reduces the quantity of insulin required to maintain normal blood glucose levels by stimulating glucose transport in adipocytes.
L-Tryptophan, acting via serotonergic neurons in hypothalamic feeding center, alters satiety and food preference, decreases carbohydrate cravings, carbohydrate intake, and daily energy intake, and promotes weight loss.
L-Tryptophan, either endogenous or exogenous, decreases craving. Tryptophan levels are reduced in obese individuals (by 18-25%) and dietary tryptophan administration suppresses carbohydrate craving (by 40%).
L-Tryptophan increases insulin and incretins secretion. The effect results in better glycemic control in diabetics.
Cayenne pepper significantly reduces weight (by 2%) and fat mass (by 7.8%) by increasing energy expenditure (by 13%) and decreasing ad libitum food intake resulting in ~960 calorie deficit per day. In an average 118 kg (260 lb) client, this is 2.4 kg (5.3 lbs) weight loss, 9.2 kg (20 lbs) fat loss, and 4 kg (8.8 lbs) increase in lean mass.
Cayenne pepper reduces cravings by 13.9% as a result of improved glycaemic control and reduced ghrelin levels.
Cayenne pepper reduces postprandial blood glucose levels by 10% resulting in improved glucose control and decreased risk of long-term complications.
Citrus aurantium decreases weight by up to 2.4 kg (5.3 lbs) in 1 week. Citrus aurantium increases the overall metabolism of fats and lipids by increasing epinephrine stimulation and increases the thermic effect of food by 29% in women.
Citrus aurantium decreases cravings by increasing the synthesis of insulin and dopamine, improving insulin sensitivity, suppressing ghrelin synthesis, protecting the liver from oxidative stress, and decreasing depression and anxiety.
Citrus aurantium improves insulin sensitivity and its synthesis by decreasing proliferation of adipocytes and fat accumulation. It also protects the liver from oxidative stress thus improving its ability to metabolize glucose.
Theobromine may have weight loss potential by enhancing other weight loss drugs and reducing body fat percentage.
Theobromine may reduce cravings by inhibiting the synergism between factors involved in cravings.
Theobromine reduces insulin resistance and also the risk of long term complications in diabetic individuals, such as vascular, renal, and ocular complications.
Salicin decreases weight by inhibiting the inflammation of adipocytes and increasing the release of fatty acids.
Salicin reduces cravings by improving glycemic control and increasing the concentration of tryptophan and serotonin released from the brain.
Salicin increases the secretion and sensitivity of insulin and protects the pancreas from inflammatory actions resulting in better glycemic control.
5-HTP (750mg to 900mg per day) increases satiety and decreases carbohydrate and food intake, promoting weight loss.
Serotonin decrease in the brain induces craving for carbohydrates and 5-HTP prevents craving.
Brain tryptophan is decreased in diabetic patients. Although 5-HTP is not shown to decrease blood glucose in diabetics in human studies, it has other beneficial effects in these patients including weight loss.