Supporting Clinical Research on Diabetes in GLOBESITY Bootcamp for the Obese Authors: Marcus Free MD, Rouzbeh Motiei-Langroudi MD, Waqar Ahmad PhD, Kelly Daly RDN, and Don Juravin (Don Karl Juravin). The Effects of GBA Regimen on Diabetes The GBA regimen is effective for diabetics as its ingredients decrease fasting glucose, postprandial glucose, and HbA1C, and […]
Sugar is made from equal parts of fructose and glucose. Almost all sugars and sweeteners activate the brain reward system, but to different extents. For instance, fructose consumption is accompanied by a higher activity rise in the brain reward system and less satiety inducing. The effect is seen to a relatively less extent in glucose, saccharin, and sucralose.
The common definition considers red meat as a meat with a darker color before and after cooking. However, in nutrition, red meat is defined as any meat that has more myoglobin than white meat. Red meat is defined as all meats obtained from mammals (regardless of cut or age) as they have more myoglobin (United States Department of Agriculture). This includes beef, veal, lamb, pork, and also a leg of chicken and turkey (the latter are considered white by common definition). Fish and poultry (excluding legs) are considered white meat.
Post-dinner snacking leads to weight gain through the increased caloric intake (Waller, 2004). Nocturnal snacking increases sugar levels. When sugar levels are increased, hormones such as insulin, ghrelin, and leptin, are activated and specific systems in the body begin to work (Kalergis, 2003). As the body becomes more alert through glucose metabolism, it may be difficult to switch off and fall asleep (Kristen, 2007). As shown in our other document, inadequate sleep causes weight gain. Women and men consume 15.3% and 9.2% more calories when deprived of sleep, respectively (St-Onge, 2011).
Theobromine may have weight loss potential by enhancing other weight loss drugs and reducing body fat percentage.
Theobromine may reduce cravings by inhibiting the synergism between factors involved in cravings.
Theobromine reduces insulin resistance and also the risk of long term complications in diabetic individuals, such as vascular, renal, and ocular complications.
Salicin decreases weight by inhibiting the inflammation of adipocytes and increasing the release of fatty acids.
Salicin reduces cravings by improving glycemic control and increasing the concentration of tryptophan and serotonin released from the brain.
Salicin increases the secretion and sensitivity of insulin and protects the pancreas from inflammatory actions resulting in better glycemic control.
5-HTP (750mg to 900mg per day) increases satiety and decreases carbohydrate and food intake, promoting weight loss.
Serotonin decrease in the brain induces craving for carbohydrates and 5-HTP prevents craving.
Brain tryptophan is decreased in diabetic patients. Although 5-HTP is not shown to decrease blood glucose in diabetics in human studies, it has other beneficial effects in these patients including weight loss.
Silicon dioxide improves metabolism and calorie burning in humans resulting in weight reduction.
Silicon Dioxide prevents the development of spontaneous diabetes in rats, possibly through enhancing host mechanisms effective in preventing the destruction of pancreatic beta cells.
Magnesium supplementation in obese patients promotes weight loss and prevents complications of weight-loss regimens.
Magnesium supplementation reduces cravings as a result of improved glucose control and increased synthesis and sensitivity of serotonin.
Decreased magnesium levels increase the risk of diabetes. In contrast, magnesium supplementation in diabetic patients decreases fasting plasma glucose, HbA1c, and weight and therefore helps to control diabetes.
Green Camellia Sinensis decreases body weight (by 4.6%), abdominal fat (by 7.7%), and waist circumference (by 4.5%) as a result of increased thermogenesis and fat oxidation.
Green Camellia Sinensis decreases cravings by improving insulin sensitivity and glucose metabolism, protecting brain centers sensitive to dopamine and serotonin from oxidative stress and stabilizing mood.
Green Camellia Sinensis decreases the risk of diabetes (by 33%) by reducing HbA1C levels, improving glucose metabolism, and increasing insulin sensitivity by 13%.