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Science of Weight Loss Supplements

The world’s most comprehensive weight loss supplements has four years of research behind it. The research covered 10,000+ clinical & reviews and cited 1,000+ researches for health professionals.
Effects of Sugar Balancing on Weight Reduction, Cravings and Diabetes

Sugar Balancing Effects on Weight Reduction and Diabetes in GLOBESITY Bootcamp for the Obese

A new ‘yellow’ pill is introduced by our lab which has blood glucose-lowering benefits. Its ingredients include Banaba leaf extract, Bilberry fruit extract, Bitter melon fruit extract, Cinnamon bark extract, Chromium, Fenugreek seed extract, Gymnema Sylvestre leaf extract, Jambolan fruit extract, Pterocarpus marsupium bark extract, Tinospora Cordifolia leaf extract, Vanadyl sulfate, and Zinc.

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Effects of Propionate on Weight Reduction Cravings and Diabetes

Propionate Effects on Weight Reduction, Cravings and Diabetes in GLOBESITY Bootcamp for the Obese

Propionate produced in the gut as a result of bacterial fermentation reduces energy intake and appetite, regulates adipogenesis, and reduces adipose tissue inflammation, finally resulting in weight loss.
Propionate produced in the gut as a result of bacterial fermentation reduces cravings for carbohydrates.
Propionate produced in the gut as a result of bacterial fermentation increases insulin and insulin sensitivity, resulting in prevention and better control of diabetes.

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Effects of Vitamin C on Weight Reduction Cravings and Diabetes

Vitamin C Effects on Weight Reduction, Cravings and Diabetes in GLOBESITY Bootcamp for the Obese

Vitamin C decreases weight by increasing fat metabolism by 30% and reducing the inflammation of adipocytes. Vitamin C also increases the concentration of adiponectin, leptin, and insulin sensitivity.
Vitamin C decreases cravings by improving glycemic control and repairing and protecting brain centers responsible for serotonin and leptin sensitivity.
Vitamin C improves diabetes control by improving insulin sensitivity, glycemic control, oxidative stress, and immune responses.

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Effects of L-Tryptophan on Weight Reduction

L-Tryptophan Effects on Weight Reduction, Cravings and Diabetes in GLOBESITY Bootcamp for the Obese

L-Tryptophan, acting via serotonergic neurons in hypothalamic feeding center, alters satiety and food preference, decreases carbohydrate cravings, carbohydrate intake, and daily energy intake, and promotes weight loss.
L-Tryptophan, either endogenous or exogenous, decreases craving. Tryptophan levels are reduced in obese individuals (by 18-25%) and dietary tryptophan administration suppresses carbohydrate craving (by 40%).
L-Tryptophan increases insulin and incretins secretion. The effect results in better glycemic control in diabetics.

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Effects of Cayenne Pepper on Weight Reduction

Cayenne Pepper Effects on Weight Reduction, Cravings and Diabetes in GLOBESITY Bootcamp

Cayenne pepper significantly reduces weight (by 2%) and fat mass (by 7.8%) by increasing energy expenditure (by 13%) and decreasing ad libitum food intake resulting in ~960 calorie deficit per day. In an average 118 kg (260 lb) client, this is 2.4 kg (5.3 lbs) weight loss, 9.2 kg (20 lbs) fat loss, and 4 kg (8.8 lbs) increase in lean mass.
Cayenne pepper reduces cravings by 13.9% as a result of improved glycaemic control and reduced ghrelin levels.
Cayenne pepper reduces postprandial blood glucose levels by 10% resulting in improved glucose control and decreased risk of long-term complications.

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Effects of Citrus Aurantium on Weight Reduction

Citrus Aurantium Effects on Weight Reduction, Cravings and Diabetes in GLOBESITY Bootcamp for the Obese

Citrus aurantium decreases weight by up to 2.4 kg (5.3 lbs) in 1 week. Citrus aurantium increases the overall metabolism of fats and lipids by increasing epinephrine stimulation and increases the thermic effect of food by 29% in women.
Citrus aurantium decreases cravings by increasing the synthesis of insulin and dopamine, improving insulin sensitivity, suppressing ghrelin synthesis, protecting the liver from oxidative stress, and decreasing depression and anxiety.
Citrus aurantium improves insulin sensitivity and its synthesis by decreasing proliferation of adipocytes and fat accumulation. It also protects the liver from oxidative stress thus improving its ability to metabolize glucose.

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Effects of  Salix Alba. L (White Willow Bark) on Weight Reduction

Salix Alba. L Effects on Weight Reduction, Cravings and Diabetes in GLOBESITY Bootcamp for the Obese

Salicin decreases weight by inhibiting the inflammation of adipocytes and increasing the release of fatty acids.
Salicin reduces cravings by improving glycemic control and increasing the concentration of tryptophan and serotonin released from the brain.
Salicin increases the secretion and sensitivity of insulin and protects the pancreas from inflammatory actions resulting in better glycemic control.

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Effects of 5-HTP on Weight Reduction

5-HTP Effects on Weight Reduction, Cravings and Diabetes in GLOBESITY Bootcamp for the Obese

5-HTP (750mg to 900mg per day) increases satiety and decreases carbohydrate and food intake, promoting weight loss.
Serotonin decrease in the brain induces craving for carbohydrates and 5-HTP prevents craving.
Brain tryptophan is decreased in diabetic patients. Although 5-HTP is not shown to decrease blood glucose in diabetics in human studies, it has other beneficial effects in these patients including weight loss.

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Effects of Magnesium on Weight Reduction

Magnesium Effects on Weight Reduction, Cravings and Diabetes in GLOBESITY Bootcamp for the Obese

Magnesium supplementation in obese patients promotes weight loss and prevents complications of weight-loss regimens. 
Magnesium supplementation reduces cravings as a result of improved glucose control and increased synthesis and sensitivity of serotonin. 
Decreased magnesium levels increase the risk of diabetes. In contrast, magnesium supplementation in diabetic patients decreases fasting plasma glucose, HbA1c, and weight and therefore helps to control diabetes.

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Effects of Green Camellia Sinensis on Weight Reduction

Green Camellia Sinensis Effects on Weight Reduction, Cravings and Diabetes in GLOBESITY Bootcamp for the Obese

Green Camellia Sinensis decreases body weight (by 4.6%), abdominal fat (by 7.7%), and waist circumference (by 4.5%) as a result of increased thermogenesis and fat oxidation.
Green Camellia Sinensis decreases cravings by improving insulin sensitivity and glucose metabolism, protecting brain centers sensitive to dopamine and serotonin from oxidative stress and stabilizing mood. 
Green Camellia Sinensis decreases the risk of diabetes (by 33%) by reducing HbA1C levels, improving glucose metabolism, and increasing insulin sensitivity by 13%.

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Effects of L-Tyrosine on Weight Reduction

L-Tyrosine Effects on Weight Reduction, Cravings and Diabetes in GLOBESITY Bootcamp for the Obese

L-Tyrosine is a precursor for dopamine and norepinephrine, which may help to promote weight loss through increased body activity and thermogenesis and decreased appetite.
Tyrosine (aka 4-hydroxyphenylalanine) is a non-essential amino acid used in the synthesis of certain neurotransmitters including dopamine, norepinephrine and epinephrine, as well as thyroid hormones thyroxine and triiodothyronine (Rosebrough 1994).

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Effects of Higenamine on Weight Reduction

Higenamine Effects on Weight Reduction, Cravings and Diabetes in GLOBESITY Bootcamp for the Obese

Higenamine stimulates fat burning and energy expenditure and reduces energy absorption by slowing gastric motility, resulting in weight loss and a healthier body fat ratio.
Higenamine decreases hormones involved with hunger and cravings such as dopamine, ghrelin, and neuropeptide.
Higenamine improves insulin secretion and sensitivity and blood glucose levels and benefits diabetics by increasing the glucose uptake into cells by up to 200%. 

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Effects of Naringin on Weight Reduction

Naringin Effects on Weight Reduction, Cravings and Diabetes in GLOBESITY Bootcamp for the Obese

Naringin decreases weight by increasing fat metabolism, decreasing inflammation of adipocytes, reducing hunger, and protecting the liver from oxidative stress. 
Naringin decreases cravings by normalizing blood glucose levels, reducing the secretion of ghrelin, and decreasing the sensitivity of brain centers to dopamine and serotonin. 
Naringin improves glycemic control by protecting the liver from oxidative stress, improving glucose metabolism in the liver, improving glucose uptake from the blood, enhancing the secretion of insulin from the pancreas, and reducing insulin resistance. 

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Effects of Yohimbine on Weight Reduction, Craving and Diabetes

Yohimbine Effects on Weight Reduction, Cravings and Diabetes in GLOBESITY Bootcamp for the Obese

Yohimbine is found naturally in the Pausinystalia Yohimbe tree and the Rauwolfia family of plants (Singh 2004). Yohimbine is best known for its fat burning and appetite suppressing properties.
Yohimbine (10mg twice daily) reduces fat percentage by 2.1% over three weeks (Ostojic 2006). In an individual with an average 45 kg (100 lb) overweight, this is 17 kg (37.5 lbs) fat reduction per year before any further dietary or exercise changes.
Yohimbine suppresses appetite and reduces food intake by 38% to 44% (Callahan 1984).

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Effects of Vitamin D on Weight Reduction

Vitamin D Effects on Weight Reduction, Cravings and Diabetes in GLOBESITY Bootcamp for the Obese

Vitamin D supplementation causes weight loss of up to 12.3 lbs (5.6 kg) in 2 years. Vitamin D status is inversely associated with total body fat percentage, BMI, waist circumference, and skinfolds. 
Vitamin D deficiency is associated with increased cravings for fatty foods. Vitamin D decreases cravings by increasing the ratio of healthy to unhealthy gut flora and protecting brain centers sensitive to serotonin and dopamine. 
Vitamin D deficiency decreases insulin secretion by 48%, disturbs glycemic control, and increases insulin resistance. Vitamin D supplementation improves the secretion of insulin from the pancreas. 

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Effects of Vitamin B6 on Weight Reduction, Craving and Diabetes

Vitamin B6 Effects on Weight Reduction, Cravings and Diabetes in GLOBESITY Bootcamp for the Obese

Vitamin B6 (Pyridoxine) is a water-soluble vitamin, which is best obtained from beans, poultry, fish, and dark leafy greens. Vitamin B6 is significant to protein, fat, and carbohydrate metabolism and the creation of red blood cells. It regulates mood and reduces stress by promoting neurotransmitters (serotonin, dopamine, gamma-aminobutyric acid) production, which in turn decreases cravings, preventing emotional eating, and weight gain. It is also important for thought processing and healthy brain development. Vitamin B6 enhances insulin’s effect on blood glucose and glycemic index in diabetes, which leads to higher glucose-lowering potency and better glucose control.

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Effects of Vitamin B12 on Weight Reduction, Craving and Diabetes

Vitamin B12 Effects on Weight Reduction, Cravings and Diabetes in GLOBESITY Bootcamp for the Obese

Vitamin B12 (Cobalamin) is a water-soluble vitamin, found naturally in a wide variety of animal foods (meats, fish, poultry, eggs, and dairy). Vitamin B12 helps convert food into glucose, which gives energy. Vitamin B12 increases the metabolism of fats and glucose, boosting energy production, which in turn decreases weight gain by muscle production and fat loss. It also helps in the production of red blood cells and DNA, as well as the proper functioning of the central nervous system. It promotes high levels of neurotransmitters such as serotonin and dopamine, preventing depression and emotional eating. 

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Effects of Chromium on Weight Reduction

Chromium Effects on Weight Reduction, Cravings and Diabetes in GLOBESITY Bootcamp for the Obese

Chromium is a low-dose mineral present in many foods (broccoli, potatoes, whole-grain products, beef, and poultry). Chromium Picolinate is the safest form of Chromium found in dietary supplements. It promotes the metabolism of carbohydrates and fats by enhancing the potency of the hormone insulin, which in turn controls the absorption of amino acids. Sufficient Chromium improves the lowering of blood sugar, preventing the risk of type 2 diabetes. Chromium also allows minerals to absorb better by surrounding it with neutral molecules, which allows passing into the cell membrane. 

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Effects of Fibersol on Weight Reduction

Fibersol Effects on Weight Reduction, Cravings and Diabetes in GLOBESITY Bootcamp for the Obese

Fibersol is a digestion-resistant maltodextrin and a low viscosity soluble dietary fiber (90%), drawn from corn starch by proprietary method. Fibersol’s molecular bonds are indigestible, allowing digestion-resistant maltodextrin to be a healthy replacement for sugar in most foods and beverages. Fibersol’s starch linkages remain in the digestive tract, which in turn increases satiety hormones such as peptide YY (PYY) and glucose-like peptide-1 (GLP-1). It boosts essential fibers to food while reducing caloric intake, resulting in fullness for a long period of time. Thus, Fibersol can delay hunger, and ultimately reduce weight. 

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Inulin Effects On Weight Reduction, Cravings And Diabetes in GLOBESITY Bootcamp for the Obese

Inulin Effects on Weight Reduction, Cravings and Diabetes in GLOBESITY Bootcamp for the Obese

Inulin is a soluble fiber found in 36,000 plant species (wheat, onion, banana, garlic, asparagus, etc.) and in some bacteria and fungi. The chicory roots are the richest source of inulin. Several manufactured forms of inulin are Chicory inulin and High-Performance (HP) inulin. In 2018 the FDA approved inulin as a dietary fiber component used to increase the nutritional value of processed food products in the United States. Inulin stimulates growth of beneficial bacteria, which in turn helps improve bowel function and gut health, curb appetite, and boosts immunity.

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Beta Glucan Effects On Weight Reduction, Cravings And Diabetes in GLOBESITY Bootcamp for the Obese

Beta Glucan Effects on Weight Reduction, Cravings and Diabetes in GLOBESITY Bootcamp for the Obese

Beta Glucan is a soluble dietary fiber found naturally in cereal grains, yeast, and in medicinal mushrooms (cordyceps, reishi, shitake, and maitake). Among its sources, barley has the highest Beta Glucan content. Beta Glucan is a polysaccharide that promotes good health by reducing cholesterol, and controls blood sugar levels. Beta Glucan lowers blood cholesterol by preventing the absorption of cholesterol from food in the stomach and intestines. If injected, Beta Glucan stimulates the immune system by growing chemicals which prevent infection. Beta Glucan also helps with constipation and bowel issues, preserves healthy intestinal bacteria, and helps regulate weight.

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Guar Gum Effects On Weight Reduction, Cravings And Diabetes in GLOBESITY Bootcamp for the Obese

Guar Gum Effects On Weight Reduction, Cravings And Diabetes in GLOBESITY Bootcamp for the Obese

Guar gum decreases body weight by 1.8 lbs (~0.81 kg) in overweight adults and those with additional risk factors for cardiovascular disease (Jovanovski 2020).
Guar gum increases satiety for 10 hours (Faris 1998).
Guar gum decreases daily energy intake by 310 calories (Pasman 1997b). That is a weight loss of ~2.5 kg (5.3 lbs) per month or 30 kg (66 lbs) per year.
Guar gum increases the ratio of the healthy to unhealthy gut flora by 100% to 1,000% (Fak 2015, Ohashi 2015, Berger 2014, Okubo 1994). An unhealthy microbiome promotes sugar cravings (Roberfroid 2010).

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